Document Type


Date of Award



College of Science, Engineering, and Technology (COSET)

Degree Name

MS in Biology

First Advisor

Professor Halcyon O. Watkins


This study sought to evaluate two groups of rats (Dahl salt-sensitive and Dahl salt-resistant) by using either or both 8% high salt rat chow, regular rat chow, 10% ethanol and tap water. This research began by obtaining 8 male Dahl rats (4 salt-sensitive and 4 salt-resistant). The rats followed the following diet. In Group I (salt-sensitive, numbered 1-4), Rat #1 was given rat chow plus tap water. Rat #2 was given 8% high salt rat chow plus tap water. Rat #3 was given rat chow plus 10% ethanol, and Rat #4 was given 8% high salt rat chow plus 10% ethanol. In Group II, (salt-resistant rats, numbered 7- 10), received an identical diet, respectively. These diets were measured by testing the K+ and Cr level using the reflotion, observing the urine volume output and dissection of each rat to remove the kidney and the adrenal gland. The salt-sensitive rats showed its susceptibility to salt hypertension by gradually becoming hypertensive (an increase in urine output), whereas the salt-resistant rats showed great resistance to salt hypertension by having no significant change in urine output